BOTH POSITIVE AND NEGATIVE SELECTION PRESSURES CONTRIBUTE TO THE POLYMORPHISM PATTERN OF THE DUPLICATED HUMAN CYP21A2 GENE.

Both positive and negative selection pressures contribute to the polymorphism pattern of the duplicated human CYP21A2 gene.

The human steroid 21-hydroxylase gene (CYP21A2) participates in cortisol and aldosterone biosynthesis, and resides together with its paralogous (duplicated) pseudogene in a multiallelic copy number variation (CNV), called RCCX CNV.Concerted evolution caused by non-allelic gene conversion has been described in great ape CYP21 genes, and the same con

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Virtual Sensing of Nitrite: A Novel Control for Safe Denitrification in Recirculating Aquaculture Systems (RASs)

Recirculating aquaculture system (RAS) technology is seen worldwide as a solution for sustainable fish production.However, there are still deficiencies in the process technology imperiling consistent operation and thus economic results.Drawbacks are linked to essential processes of the water treatment systems such as denitrification.Nitrogenous was

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Harmonic enhancement to optimize EOG based ocular activity decoding: A hybrid approach with harmonic source separation and EEMD

Intelligent robotic systems for patients with motor impairments have gained significant interest over the past few years.Various sensor types and human-machine interface (HMI) methods have been developed; however, most research in this area has focused on eye-blink-based binary control with minimal electrode placements.This approach restricts the c

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